TACO Protocol

As a participant in the TACO study it is required that your institution be monitored by the IROC Houston.

• Please complete and submit a on line demographics form, if you are not currently monitored by the IROC Houston.

• Each institution will receive OSLD for their megavoltage photon beams if you are not already being monitored as part of your membership in an NCI-sponsered cooperative study group.

• For International Institutions:

o   If your institution is not a member of an NCI funded clinical trial group you will need to submit all data to ANZGOG directly.

o   If your institution is a member of an NCI funded clinical trial group you will need to submit all data directly to the IROC Houston.

External Beam Radiation Therapy:

Please submit the following: (Data Submission Check List)

• Complete Case Report Form (CRF)

• Portal Films

• Daily treatment records

• DVH in color with all of the critical structure displayed

• Treatment plan including isodose distribution through the center of the treatment volume

• Beams Eye Views of each field

• All dosimetry calculations

• A completed online External Beam Summary Form

Brachytherapy:

Please submit the following:

• Complete Case Report Form (CRF)

• Simulator films (include magnification factors), digitally reconstructed radiographs(DRRs), CTs, MRIs or US images with applicator in-situ for each intracavitary placement. If providing DRRs please provide an AP and Lateral view in order for us to be able to determine point A and B dose. Please see the file linked here which explains exactly what views are needed in order for us to be able to determine the bladder and rectal doses.

• Treatment plan to include source activities, dwell times, dwell positions and isodose lines

• A completed online Gynecological Brachytherapy Protocol Compliance Form

Data Submission:

• For International Institutions:

o   If your institution is not a member of an NCI funded clinical trial group you will need to submit all data to ANZGOG directly.

o   If your institution is a member of an NCI funded clinical trial group you will need to submit all data directly to the IROC Houston.

• For United States Institutions, you will need to submit all data directly to the IROC Houston.

There are several different methods that data can be sent to the IROC Houston:

• A hard copy of the data can be sent via snail mail or converted to pdf and emailed to the IROC Houston.

• CTs, MRIs and US images can either be burned to a CD and snail mailed or can be sent electronically through the IROC Houstons ftp site.

• If films are taken for brachytherapy they can be sent via snail mail or electronically as long as a magnification factor can be determined. Without a magnification the IROC Houston is unable to perform a recalculation of brachytherapy dose.

Important Information